PTGS2 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Prostaglandin G/H synthase 2, Cyclooxygenase-2, COX-2, PHS II, Prostaglandin H2 synthase 2, PGH synthase 2, PGHS-2, Prostaglandin-endoperoxide synthase 2, PTGS2, COX2 | Тип антител | Recombinant Antibody | Species | Human | UniProt ID | P35354 | Иммуноген | A synthesized peptide derived from human PTGS2 | Видовая специфичность | Human | Применение | ELISA | Клональность | Monoclonal | Изотип | Rabbit IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Affinity-chromatography | Области исследований | Cardiovascular | Аббревиатура | Prostaglandin G/H synthase 2 | Примечание | Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis (PubMed:26859324, PubMed:27226593). Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis. | Ссылка на страницу на сайте производителя | ссылка | | |
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