| Объем | 50 мкл |
| Синонимы | RNA binding protein, fox-1 homolog (C. elegans) 3 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | A6NFN3 |
| Иммуноген | Synthetic peptide of human RBFOX3 |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:15-1:50 |
| Примечание | Immunoprecipitation and mass spectrometry of the two major NeuN species at 45–50 kDa identified both as the RNA binding protein Rbfox3 (a member of the Fox family of alternative splicing factors), confirming and extending the identification of the 45 kDa band as Rbfox3. Mapping of the anti-NeuN reactive epitopes in both R3hdm2 and Rbfox3 reveals a common proline- and glutamine-rich domain that lies at the N-terminus of the Rbfox3 protein. Nuclear Rbfox3 isoforms can also enhance the inclusion of cryptic exons in the Rbfox2 mRNA, resulting in nonsense-mediated decay of the message, thereby contributing to the negative regulation of Rbfox2 by Rbfox3 through a novel mechanism. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Tags & Cell Markers |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA070474(RBFOX3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
 |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA070474(RBFOX3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
 |
Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane: Jurkat cells, Primary antibody: CSB-PA070474(RBFOX3 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
 |
| | |
Наименование: RBFOX3 Antibody.