RCOR1 Antibody, FITC conjugatedСпецификацияОбъем | 50 мкг | Синонимы | REST corepressor 1 (Protein CoREST), RCOR1, KIAA0071 RCOR | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9UKL0 | Иммуноген | Recombinant Human REST corepressor 1 protein (394-482AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | FITC | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | REST corepressor 1 | Области исследований | Epigenetics and Nuclear Signaling | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 50 мкг | Кат. номер: | CSB-PA019515HC01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: RCOR1 Antibody, FITC conjugated. Примечание: дополнительная информация (на английском языке). |
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