Объем | 100 мкл |
Синонимы | BSP-1, BSP1, Dwarfin-A, Dwf-A, JV4-1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q15797 |
Иммуноген | Synthesized non-phosphopeptide derived from human Smad1 around the phosphorylation site of serine 187 (P-H-S(p)-P-N). |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200 |
Примечание | <p>Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.<br /><br />Riggins G.J., Nat. Genet. 13:347-349(1996).<br />Liu F., Nature 381:620-623(1996).<br />Hoodless P.A., Cell 85:489-500(1996)</p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Cancer,Signal transduction,Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from JK and K562 cells, using Smad1 (Ab-187) antibody.
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Immunofluorescence analysis of HeLa cells, using Smad1 (Ab-187) antibody.
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