REST Antibody, Biotin conjugatedСпецификация| Объем | 100 мкг | | Синонимы | RE1-silencing transcription factor (Neural-restrictive silencer factor) (X2 box repressor), REST, NRSF XBR | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q13127 | | Иммуноген | Recombinant Human RE1-silencing transcription factor protein (250-350AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA | | Примечание | Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Biotin | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | RE1-silencing transcription factor | | Области исследований | Epigenetics and Nuclear Signaling, Neuroscience | | Ссылка на страницу на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкг | | Кат. номер: | CSB-PA019571LD01HU | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: REST Antibody, Biotin conjugated.
Примечание: дополнительная информация (на английском языке). |
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