| Объем | 50 мкл |
| Синонимы | Protein quaking (Hqk) (HqkI), QKI, HKQ |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q96PU8 |
| Иммуноген | Recombinant Human Protein quaking protein (1-341AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Абревеатура | Protein quaking |
| Области исследований | Epigenetics and Nuclear Signaling, Neuroscience, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: QKI antibody at 1.92µg/ml
Lane 1: HL60 whole cell lysate
Lane 2: K562 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 38, 37, 36 kDa
Observed band size: 38, 70 kDa
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Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA842739ESR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA842739ESR2HU at dilution of 1:100
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Наименование: QKI Antibody.