RAB11B AntibodyСпецификация| Объем | 100 мкг | | Синонимы | Ras-related protein Rab-11B (GTP-binding protein YPT3), RAB11B, YPT3 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q15907 | | Иммуноген | Recombinant Human Ras-related protein Rab-11B protein (2-215AA) | | Источник | Rabbit | | Видовая специфичность | Human, Rat | | Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 | | Примечание | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Области исследований | Others | | Ссылка на страницу на сайте производителя | ссылка | Western blot
All lanes: RAB11B antibody at 2µg/ml
Lane 1: Hela cells
Lane 2: Rat gonad tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 25, 20 kDa
Observed band size: 25 kDa
 | Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA614903LA01HU at dilution of 1:100
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Наименование: RAB11B Antibody.