RFX3 Antibody, Biotin conjugated

Спецификация

Объем	100 мкг
Синонимы	Transcription factor RFX3 (Regulatory factor X 3), RFX3
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P48380
Иммуноген	Recombinant Human Transcription factor RFX3 protein (201-413AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left-right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly (DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility (DNAH11, DNAH9 and DNAH5). Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP (polypeptide-producing) cells. Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes. Acts as a transcription factor. Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Области исследований	Epigenetics and Nuclear Signaling
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкг
	Кат. номер:	CSB-PA019612LD01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: RFX3 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).