Объем | 100 мкл |
Синонимы | RAB3 GTPase activating protein 2 (non-catalytic), RAB3-GAP150, RAB3GAP150, RBGPR, RGAP-iso |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9H2M9 |
Иммуноген | Synthesized peptide derived from internal of human. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
Примечание | Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.<br/><br/>Nagano F., J. Biol. Chem. 273:24781-24785(1998).<br/>Xu X., Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.<br/>Nagase T., DNA Res. 5:355-364(1998).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Neuroscience,Developmental biology,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COS cells, using RAB3GAP2 antibody.
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using RAB3GAP2 antibody.
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