SOCS1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Suppressor of cytokine signaling 1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | O15524 | Иммуноген | Synthetic peptide of human SOCS1 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:100-1:300 | Примечание | This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Epigenetics and Nuclear Signaling,Immunology,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA277236(SOCS1 Antibody) at dilution 1/90, on the right is treated with synthetic peptide. (Original magnification: ?200)
| The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA277236(SOCS1 Antibody) at dilution 1/90, on the right is treated with synthetic peptide. (Original magnification: ?200)
| Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: HT29 cells, 231 cells, Primary antibody: CSB-PA277236(SOCS1 Antibody) at dilution 1/1700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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