Объем | 100 мкл |
Синонимы | ring finger protein 20, E3 ubiquitin protein ligase |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q5VTR2 |
Иммуноген | Fusion protein of human RNF20 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:10-1:50 |
Примечание | The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA942697(RNF20 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ?200)
|
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA942697(RNF20 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ?200)
|
Gel: 6%SDS-PAGE, Lysate: 40 ?g, Lane 1-6: Hela cells, Jurkat cells, 231 cells, A375 cells, A172 cells, Lovo cells, Primary antibody: CSB-PA942697(RNF20 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
|
| |