| Объем | 100 мкл |
| Синонимы | Apoptosis regulator BAX, membrane isoform alpha, BAXA, Bcl2-associated X protein, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q07812 |
| Иммуноген | Synthesized non-phosphopeptide derived from human Bax around the phosphorylation site of threonine 167 (F-G-T(p)-P-T). |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
| Примечание | Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.<br/><br/>Oltvai Z.N., Cell 74:609-619(1993).<br/>Cuddeback S.M., J. Biol. Chem. 276:20559-20565(2001).<br/>Guo B., Nature 423:456-461(2003)<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cancer,Cell biology,Metabolism |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells, using Bax (Ab-167) antibody.
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Immunofluorescence analysis of LOVO cells, using Bax (Ab-167) antibody.
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Наименование: BAX (Ab-167) Antibody.