BBS5 Antibody, HRP conjugatedСпецификация| Объем | 50 мкг | | Синонимы | Bardet-Biedl syndrome 5 protein, BBS5 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q8N3I7 | | Иммуноген | Recombinant Human Bardet-Biedl syndrome 5 protein (224-317AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA | | Примечание | The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | HRP | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | Bardet-Biedl syndrome 5 protein | | Ссылка на страницу на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 50 мкг | | Кат. номер: | CSB-PA847625LB01HU | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: BBS5 Antibody, HRP conjugated.
Примечание: дополнительная информация (на английском языке). |
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