SGO1 Antibody, Biotin conjugatedСпецификацияОбъем | 100 мкг | Синонимы | Shugoshin 1 (Serologically defined breast cancer antigen NY-BR-85) (Shugoshin-like 1), SGO1, SGOL1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q5FBB7 | Иммуноген | Recombinant Human Shugoshin 1 protein (260-439AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase. Essential for proper chromosome segregation during mitosis and this function requires interaction with PPP2R1A. Its phosphorylated form is necessary for chromosome congression and for the proper attachment of spindle microtubule to the kinetochore. Necessary for kinetochore localization of PLK1 and CENPF. May play a role in the tension sensing mechanism of the spindle-assembly checkpoint by regulating PLK1 kinetochore affinity. Isoform 3 plays a role in maintaining centriole cohesion involved in controlling spindle pole integrity. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Biotin | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | Shugoshin 1 | Области исследований | Epigenetics and Nuclear Signaling | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 100 мкг | Кат. номер: | CSB-PA688764LD01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: SGO1 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке). |
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