SS18L1 Antibody, FITC conjugated

Спецификация

Объем	50 мкг
Синонимы	Calcium-responsive transactivator (SS18-like protein 1) (SYT homolog 1), SS18L1, CREST KIAA0693
Клональность	Polyclonal Antibody
Организм	Human
uniprot	O75177
Иммуноген	Recombinant Human Calcium-responsive transactivator protein (47-396AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity).
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	FITC
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Calcium-responsive transactivator
Области исследований	Others
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA022701LC01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: SS18L1 Antibody, FITC conjugated. Примечание: дополнительная информация (на английском языке).