SIRT3 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | NAD-dependent deacetylase sirtuin-3, mitochondrial, SIR2-like protein 3, hSIRT3, SIRT3 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9NTG7 | Иммуноген | Synthesized peptide derived from C-terminal of human SIRT3. | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, WB,WB:1:500-1:3000 | Примечание | NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.<br/><br/>Bechtel S., BMC Genomics 8:399-399(2007).<br/>Schwer B., J. Cell Biol. 158:647-657(2002).<br/>Onyango P., Proc. Natl. Acad. Sci. U.S.A. 99:13653-13658(2002).<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cardiovascular,Cell biology,Metabolism | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from COLO205 cells, using SIRT3 antibody.
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