| Объем | 50 мкл |
| Синонимы | serine/threonine kinase 40 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q8N2I9 |
| Иммуноген | Fusion protein of human STK40 |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, IHC,ELISA:1:1000-1:5000, IHC:1:50-1:200 |
| Примечание | STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFκB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFκB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFκB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Epigenetics and Nuclear Signaling,Cell biology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA158011(STK40 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA158011(STK40 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
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Наименование: STK40 Antibody.