Объем | 100 мкл |
Синонимы | E3 ubiquitin-protein ligase RNF138, EC 6.3.2.-, RING finger protein 138, Nemo-like kinase-associated RING finger protein, NLK-associated RING finger protein |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q8WVD3 |
Иммуноген | Synthesized peptide derived from internal of human RNF138. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.<br/><br/>Wang L., Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from MCF-7 cells, using RNF138 antibody.
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