Объем | 50 мкл |
Синонимы | Probable E3 SUMO-protein ligase RNF212 (EC 2.3.2.-) (Probable E3 SUMO-protein transferase RNF212) (RING finger protein 212), RNF212 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q495C1 |
Иммуноген | Recombinant Human Probable E3 SUMO-protein ligase RNF212 protein (1-297AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC, Recommended dilution: IHC:1:20-1:200 |
Примечание | SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination (By similarity). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA019872ESR2HU at dilution of 1:100
|
| |