SYNE3 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | nesprin-3, SYNE3, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q6ZMZ3 | Иммуноген | Synthesized peptide derived from internal of human C14orf49. | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, WB,WB:1:500-1:3000 | Примечание | Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.<br/><br/>Li W.B., Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.<br/>Heilig R., Nature 421:601-607(2003).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/><br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat cells, using C14orf49 antibody.
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