SLC4A11 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | BTR1, CDPD, CHED2, NABC1, SLC4A11 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q8NBS3 | Иммуноген | Synthesized peptide derived from internal of human SLC4A11. | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, WB,WB:1:500-1:3000 | Примечание | Transporter which plays an important role in sodium-mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into the thin descending limb of Henle loop to allow countercurrent multiplication by osmotic equilibration By similarity. Involved in borate homeostasis. In the absence of borate, it functions as a Na+ and OH-(H+) channel. In the presence of borate functions as an electrogenic Na+ coupled borate cotransporter.<br/><br/>Parker M.D., Biochem. Biophys. Res. Commun. 282:1103-1109(2001).<br/>Deloukas P., Nature 414:865-871(2001).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Neuroscience,Cancer,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from 3T3 cells, RAW264.7 cells and A549 cells, using SLC4A11 antibody.
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