SMAD4 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | SMAD family member 4 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q13485 | | Иммуноген | Fusion protein of human SMAD4 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:200-1:500, IHC:1:50-1:200 | | Примечание | This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cardiovascular,Metabolism,Signal transduction,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA948107(SMAD4 Antibody) at dilution 1/40. (Original magnification: ?200)
 | The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA948107(SMAD4 Antibody) at dilution 1/40. (Original magnification: ?200)
 | Gel: 10%SDS-PAGE, Lysate: 30 ?g, Lane 1-2: Human liver cancer tissue, Hela cells, Primary antibody: CSB-PA948107(SMAD4 Antibody) at dilution 1/150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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Наименование: SMAD4 Antibody.