| Объем | 100 мкл |
| Синонимы | NACP, SYN, SYUA, alpha-synuclein, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P37840 |
| Иммуноген | Peptide sequence around aa. 131~135 (E-G-Y-Q-D) derived from Human a-Synuclein. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IF,WB:1:500-1:1000, IF:1:100-1:200 |
| Примечание | May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.<br/><br/>Kozikowski AP, et al. (2006)ChemMedChem. 1(2):256-66.<br/>Jakowec MW,et al.(2001)Dev Neurosci.23(2):91-9.<br/>El-Agnaf OM,et al.(1998)FEBS Lett. 440(1-2):67-70.<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Области исследований | Neuroscience |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Hela cells using a-Synuclein(Ab-133) Antibody.
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Immunofluorescence staining of methanol-fixed Hela cells using a-Synuclein(Ab-133) Antibody.
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Наименование: SNCA (Ab-133) Antibody.