Объем | 50 мкл |
Синонимы | sperm associated antigen 6 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O75602 |
Иммуноген | Synthetic peptide of human SPAG6 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,ELISA:1:1000-1:2000, WB:1:200-1:1000 |
Примечание | The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Signal transduction,Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane: Human testis tissue, Primary antibody: CSB-PA042228(SPAG6 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
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