SRF AntibodyСпецификацияОбъем | 100 мкл | Синонимы | serum response factor (c-fos serum response element-binding transcription factor) | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P11831 | Иммуноген | Synthetic peptide of human SRF | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 | Примечание | This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Epigenetics and Nuclear Signaling,Cardiovascular,Developmental biology,Stem cells | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA555646(SRF Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ?200)
| The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA555646(SRF Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ?200)
| Gel: 10%SDS-PAGE, Lysate: 50 ?g, Lane 1-2: HT29 cells, Jurkat cells, Primary antibody: CSB-PA555646(SRF Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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