| Объем | 100 мкл |
| Синонимы | Protein name Tumor necrosis factor [Precursor], TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P01375 |
| Иммуноген | Synthesized peptide derived from internal of human TNFA. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, IHC, IF,IHC:1:50-1:100, IF:1:100-1:500 |
| Примечание | Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.<br/><br/>Neville M.J., J. Immunol. 162:4745-4754(1999).<br/>Xie T., Genome Res. 13:2621-2636(2003).<br/>Kim Y.J., Hum. Mol. Genet. 12:2541-2546(2003). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cancer,Cardiovascular,Immunology,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using TNFA antibody.
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Immunofluorescence analysis of HepG2 cells, using TNFA antibody.
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Наименование: TNF Antibody.