Объем | 50 мкл |
Синонимы | Sestrin-3, SESN3, SEST3 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P58005 |
Иммуноген | Recombinant Human Sestrin-3 protein (1-310AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC, Recommended dilution: IHC:1:20-1:200 |
Примечание | Sestrins, including sestrin-1 (PA26), sestrin-2 (Hi95), and sestrin-3, are 48 to 65 kDa cystein sulfinyl reductases and they modulate peroxide signaling and antioxidant defense. These proteins selectively reduce or repair hyperoxidized forms of typical 2-Cys peroxiredoxins within eukaryotes. Expression of these proteins is regulated by p53, a tumor suppressor protein. Sestrin 3 was identified as a forkhead box O (FoxO) target gene with antioxidant activity. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Области исследований | Cancer, Cardiovascular, Cell biology, Metabolism |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA021097ESR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA021097ESR2HU at dilution of 1:100
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