Объем | 100 мкл |
Синонимы | Tumor necrosis factor ligand superfamily member 12, TNF-related weak inducer of apoptosis, TWEAK, APO3 ligand, Tumor necrosis factor ligand superfamily member 12 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O43508 |
Иммуноген | Synthesized peptide derived from internal of human TNF12. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
Примечание | Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.<br/><br/>Chicheportiche Y., J. Biol. Chem. 272:32401-32410(1997).<br/>Marsters S.A., Curr. Biol. 8:525-528(1998).<br/>Clark H.F., Genome Res. 13:2265-2270(2003).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cancer,Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO cells, HUVEC cells and 293 cells, using TNF12 antibody.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue using TNF12 antibody.
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Immunofluorescence analysis of HeLa cells, using TNF12 antibody.
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