Объем | 100 мкл |
Синонимы | CGI-110, HSPC175, Ht006, PM14, pre-mRNA branch site protein p14 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9Y3B4 |
Иммуноген | Synthesized peptide derived from C-terminal of human SF3B14. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Necessary for the splicing of pre-mRNA. Directly contacts the pre-mRNA branch site adenosine for the first catalytic step of splicing. Enters the spliceosome and associates with the pre-mRNA branch site as part of the 17S U2 or, in the case of the minor spliceosome, as part of the 18S U11/U12 snRNP complex, and thus may facilitate the interaction of these snRNP with the branch sites of U2 and U12 respectively.<br/><br/>Will C.L., EMBO J. 20:4536-4546(2001).<br/>Lai C.-H., Genome Res. 10:703-713(2000).<br/>Zhang Q.-H., Genome Res. 10:1546-1560(2000).<br/><br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells, using SF3B14 antibody.
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