Объем | 100 мкг |
Синонимы | Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain), TRADD |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q15628 |
Иммуноген | Recombinant Human Tumor necrosis factor receptor type 1-associated DEATH domain protein (1-312AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA |
Примечание | The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | HRP |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Tumor necrosis factor receptor type 1-associated DEATH domain protein |
Области исследований | Cancer, Cardiovascular, Cell biology |
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