| Объем | 100 мкл |
| Синонимы | Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8), SIGIRR |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q6IA17 |
| Иммуноген | Recombinant Human Single Ig IL-1-related receptor protein (1-120AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Абревеатура | Single Ig IL-1-related receptor |
| Области исследований | Immunology, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: SIGIRR antibody at 1.77µg/ml
Lane 1: Mouse liver tissue
Lane 2: Mouse kidney tissue
Lane 3: MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 46, 56 kDa
Observed band size: 46 kDa
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Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA743558ESR1HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA743558ESR1HU at dilution of 1:100
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Наименование: SIGIRR Antibody.