SIK1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | salt-inducible kinase 1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P57059 | | Иммуноген | Synthetic peptide of human SIK1 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:500-1:2000, IHC:1:25-1:100 | | Примечание | SIK1 (salt-inducible kinase 1), also known as SNF1LK or MSK, is a 783 amino acid protein that contains one UBA domain and one protein kinase domain and belongs to the Ser/Thr protein kinase family. Localized to both the nucleus and the cytoplasm, SIK1 uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation. Additionally, SIK1 has a potential role in regulation of the G2/M cell cycle transition, as well as in inhibitory control of CREB protein function. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Epigenetics and Nuclear Signaling,Cardiovascular,Cell biology,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA211930(SIK1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | Gel: 6%SDS-PAGE, Lysate: 40 ?g, Lane 1-5: HT29 cells, hela cells, mouse liver tissue, A549 cells, Jurkat cells, Primary antibody: CSB-PA211930(SIK1 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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Наименование: SIK1 Antibody.