| Объем | 50 мкл |
| Синонимы | sialic acid binding Ig-like lectin 8 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9NYZ4 |
| Иммуноген | Synthetic peptide of human SIGLEC8 |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Примечание | Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Immunology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA555966(SIGLEC8 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA555966(SIGLEC8 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Наименование: SIGLEC8 Antibody.