SIRT5 Antibody, HRP conjugatedСпецификация| Объем | 100 мкг | | Синонимы | NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 3.5.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5), SIRT5, SIR2L5 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9NXA8 | | Иммуноген | Recombinant Human NAD-dependent protein deacylase sirtuin-5, mitochondrial protein (60-212AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA | | Примечание | NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins (PubMed:21908771, PubMed:22076378, PubMed:24703693). Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting (PubMed:22076378, PubMed:24703693). Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species (PubMed:24140062). Modulates ketogenesis through the desuccinylation and activation of HMGCS2 (By similarity). Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | HRP | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | NAD-dependent protein deacylase sirtuin-5, mitochondrial | | Области исследований | Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Metabolism | | Ссылка на страницу на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкг | | Кат. номер: | CSB-PA873680LB01HU | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: SIRT5 Antibody, HRP conjugated.
Примечание: дополнительная информация (на английском языке). |
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