| Объем | 50 мкг |
| Синонимы | FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16), SUPT16H, FACT140 FACTP140 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9Y5B9 |
| Иммуноген | Recombinant Human FACT complex subunit SPT16 protein (187-282AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | HRP |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | FACT complex subunit SPT16 |
| Области исследований | Epigenetics and Nuclear Signaling, Cell biology, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: SUPT16H Antibody, HRP conjugated.