| Объем | 100 мкл |
| Синонимы | TAR DNA-binding protein 43 (TDP-43), TARDBP, TDP43 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q13148 |
| Иммуноген | Recombinant Human TAR DNA-binding protein 43 protein (1-260AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, IP, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IP:1:200-1:2000 |
| Примечание | DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Epigenetics and Nuclear Signaling, Neuroscience, Microbiology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: TAR DNA-binding protein 43 antibody at 8µg/ml
Lane 1: Hela whole cell lysate
Lane 2: Mouse spleen tissue
Lane: K562 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 45, 32 kDa
Observed band size: 45 kDa
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Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA621652ESR1HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA621652ESR1HU at dilution of 1:100
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Наименование: TARDBP Antibody.