Объем | 50 мкг |
Синонимы | Telomerase-binding protein EST1A (EC 3.1.-.-) (EST1-like protein A) (Ever shorter telomeres 1A) (Smg-6 homolog) (Telomerase subunit EST1A) (hSmg5/7a), SMG6, C17orf31 EST1A KIAA0732 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q86US8 |
Иммуноген | Recombinant Human Telomerase-binding protein EST1A protein (251-511AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC, IF, Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 |
Примечание | Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Области исследований | Cancer |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA773032LA01HU at dilution of 1:100
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Immunohistochemistry analysis of human endometrial cancer using CSB-PA773032LA01HU at dilution of 1:100
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Immunofluorescent analysis of MCF-7 cells using CSB-PA773032LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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