Объем | 100 мкг |
Синонимы | Schlafen family member 11, SLFN11 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q7Z7L1 |
Иммуноген | Recombinant Human Schlafen family member 11 protein (670-821AA) |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC, IF, Recommended dilution: WB:1:500-1:5000, IHC:1:100-1:500, IF:1:50-1:500 |
Примечание | Interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis. Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner. Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides. The exact inhibition mechanism is unclear: may either sequesters tRNAs, prevents their maturation via post-transcriptional processing or accelerates their deacylation. Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA. May play a role in cell cycle arrest and/or induction of apoptosis in response to exogenously induced DNA damage. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Schlafen family member 11 |
Области исследований | Others |
Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: Mouse skeletal muscle tissue
All lanes: SLFN11 antibody at 2.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 103 kDa
Observed band size: 103 kDa
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Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA021760LA01HU at dilution of 1:100
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Immunofluorescent analysis of Hela cells using CSB-PA021760LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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