SMC6 Antibody, FITC conjugatedСпецификация| Объем | 50 мкг | | Синонимы | Structural maintenance of chromosomes protein 6, SMC protein 6, SMC-6, hSMC6, SMC6, SMC6L1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q96SB8 | | Иммуноген | Recombinant Human Structural maintenance of chromosomes protein 6 protein (309-450AA) | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA | | Примечание | Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome (PubMed:26983541). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | FITC | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | Structural maintenance of chromosomes protein 6 | | Области исследований | Epigenetics and Nuclear Signaling, Cell biology | | Ссылка на страницу на сайте производителя | ссылка | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 50 мкг | | Кат. номер: | CSB-PA836300LC01HU | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: SMC6 Antibody, FITC conjugated.
Примечание: дополнительная информация (на английском языке). |
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