| Объем | 50 мкг |
| Синонимы | Meiotic recombination protein SPO11 (EC 5.99.1.3) (Cancer/testis antigen 35) (CT35), SPO11 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9Y5K1 |
| Иммуноген | Recombinant Human Meiotic recombination protein SPO11 protein (28-109AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, Recommended dilution: WB:1:500-1:5000 |
| Примечание | Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Meiotic recombination protein SPO11 |
| Области исследований | Epigenetics and Nuclear Signaling, Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: Jurkat whole cell lysate, Raji whole cell lysate, HepG2 whole cell lysate, 293T whole cell lysate
All lanes: SPO11 antibody at 5.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 45, 41 kDa
Observed band size: 45 kDa
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Наименование: SPO11 Antibody.