Объем | 50 мкл |
Синонимы | Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein), STAM2, HBP |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O75886 |
Иммуноген | Recombinant Human Signal transducing adapter molecule 2 protein (376-525AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
Примечание | Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Абревеатура | Signal transducing adapter molecule 2 |
Области исследований | Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: STAM2 antibody at 4.09µg/ml
Lane 1: 293T whole cell lysate
Lane 2: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 59, 39 kDa
Observed band size: 59 kDa
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Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA022793ESR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA022793ESR2HU at dilution of 1:100
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