| Объем | 100 мкл |
| Синонимы | 1,25-dihydroxyvitamin D3 receptor, NR1I1, vitamin D receptor, vitamin D3 receptor |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P11473 |
| Иммуноген | Synthesized non-phosphopeptide derived from human Vitamin D3 Receptor around the phosphorylation site of serine 51 (R-R-S(p)-M-K). |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.<br/><br/>Baker A.R., Proc. Natl. Acad. Sci. U.S.A. 85:3294-3298(1988).<br/>Goto H., Biochim. Biophys. Acta 1132:103-108(1992).<br/>Miyamoto K., Mol. Endocrinol. 11:1165-1179(1997).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using Vitamin D3 Receptor (Ab-51) antibody.
 |
| | |
Наименование: VDR (Ab-51) Antibody.