| Объем | 100 мкл |
| Синонимы | Metalloreductase STEAP3, EC 1.16.1.-, Six-transmembrane epithelial antigen of prostate 3, Tumor suppressor-activated pathway protein 6, hTSAP6 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q658P3 |
| Иммуноген | Synthesized peptide derived from internal of human STEA3. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
| Примечание | Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Can also reduce of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.<br/><br/>Passer B.J., Proc. Natl. Acad. Sci. U.S.A. 100:2284-2289(2003).<br/>Korkmaz C.G., Oncogene 24:4934-4945(2005).<br/>Steiner M.S., Cancer Res. 60:4419-4425(2000). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO205 cells, using STEA3 antibody.
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Immunofluorescence analysis of HeLa cells, using STEA3 antibody.
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Наименование: STEAP3 Antibody.