WAS AntibodyСпецификацияОбъем | 100 мкл | Синонимы | THC, THC1, IMD2 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P42768 | Иммуноген | Peptide sequence around aa.289~293 (L-I-Y-D-F) derived from Human WASP. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,WB:1:500-1:1000 | Примечание | Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.<br/><br/>Kolluri R., Tolias K.F., Carpenter C.L., Rosen F.S. Proc. Natl. Acad. Sci. U.S.A. 93:5615-5618(1996)<br/> Ramesh N., Anton I.M., Hartwig J.H., Geha R.S. Proc. Natl. Acad. Sci. U.S.A. 94:14671-14676(1997)<br/>Cory G.O.C., Cramer R., Blanchoin L., Ridley A.J. Mol. Cell 11:1229-1239(2003) | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extract from Hela, JK and Raji cells using WASP Antibody
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