Объем | 100 мкл |
Синонимы | Tumor necrosis factor, alpha-induced protein 8, Head and neck tumor and metastasis-related protein, TNF-induced protein GG2-1, SCC-S2 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O95379 |
Иммуноген | Synthesized peptide derived from internal of human TFIP8. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
Примечание | Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.<br/><br/>Horrevoets A.J.G., Blood 93:3418-3431(1999).<br/>Kumar D., J. Biol. Chem. 275:2973-2978(2000).<br/>You Z., J. Biol. Chem. 276:26398-26404(2001). |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cancer,Cell biology,Immunology,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HUVEC cells, using TFIP8 antibody.
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Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using TFIP8 antibody.
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Immunofluorescence analysis of A549 cells, using TFIP8 antibody.
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