WNT1 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | wingless-type MMTV integration site family, member 1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P04628 | Иммуноген | Synthetic peptide of human WNT1 | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, WB, IHC,ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 | Примечание | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cancer,Stem cells | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA682357(WNT1 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ?200)
| Gel: 6%SDS-PAGE, Lysate: 50 ?g, Lane: HT29 cells, Primary antibody: CSB-PA682357(WNT1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
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