Объем | 100 мкл |
Синонимы | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q15750 |
Иммуноген | Fusion protein of human TAB1 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Примечание | The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Cardiovascular,Immunology,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA958657(TAB1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
|
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA958657(TAB1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
|
| |