TNFRSF1B AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Tumor necrosis factor receptor superfamily member 1B [Precursor], Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, p75 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P20333 | | Иммуноген | Synthesized peptide derived from C-terminal of human TNF Receptor II. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 | | Примечание | Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.<br/><br/>Smith C.A., Science 248:1019-1023(1990).<br/>Kohno T., Proc. Natl. Acad. Sci. U.S.A. 87:8331-8335(1990).<br/>Beltinger C.P., Genomics 35:94-100(1996).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Cell biology,Immunology,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from RAW264.7 cells, HT-29 cells and LOVO cells, using TNF Receptor II antibody.
 | Immunofluorescence analysis of HeLa cells, using TNF Receptor II antibody.
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Наименование: TNFRSF1B Antibody.