Объем | 100 мкл |
Синонимы | Y-box-binding protein 2, Germ cell-specific Y-box-binding protein, Contrin, MSY2 homolog, YBX2 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9Y2T7 |
Иммуноген | Synthesized peptide derived from internal of human YBOX2. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay By similarity.<br/><br/>Tekur S., J. Androl. 20:135-144(1999).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Developmental biology,Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO205 cells, using YBOX2 antibody.
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