Объем | 50 мкл |
Синонимы | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P62258 |
Иммуноген | Synthetic peptide of human YWHAE |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC,ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200 |
Примечание | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Neuroscience,Signal transduction,Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA903514(YWHAE Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA903514(YWHAE Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Gel: 12%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: Human brain malignant glioma tissue, Human laryngocarcinoma tissue, Primary antibody: CSB-PA903514(YWHAE Antibody) at dilution 1/1300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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